Can the same information remain readable as neural activity changes? ↗
As neural representations change, what must remain and what must a reader update to keep using the same information?
Flexible electrodes tracked the same mouse neurons over months. Aligning activity across recording days improved decoding of temporal information in a repeated movie. The analysis also used responses from the new day.
- Longitudinal tracking of the same cellsRecorded
- Alignment across recording daysRecorded
- Maintenance mechanisms in the brainUnverified
Distinguished stable long-term recording from changing representations, using new-day alignment to consider adaptive readout.
Distinguish reader adaptation from stable information components, and examine the learning that maintains their correspondence or its breakdown.