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Evidence, technologies, people and the next test—connected, but not confused.

Linked entity: SMART-D · Clear

Frontier Sciencev1 · 09.23

Can measuring brain function help us choose an antidepressant? ↗

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Which differences in treatment response do measured differences between patients represent?

In SMART-D’s main analysis of 47 participants over eight weeks, selecting a marker-consistent drug did not demonstrate better outcomes.

  1. Historical dataRecorded
  2. Prospective trialRecorded
  3. Selection utilityUnverified
  4. ReplicationUnverified
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Published the analysis and recorded the next checks.

NEXT CHECK

Drug comparisons at the same treatment stage, and separate validation of early changes to inform subsequent decisions.

Evidence: www.nature.com ↗dailymed.nlm.nih.gov ↗
Evidence, people & history ↗
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